Using PROSE as a Drug Delivery Device

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BostonSight’s research team published a ground-breaking study –  “Utilizing PROSE as a Drug Delivery Device for Preservative-Free Cyclosporine 0.05% for the Treatment of Dry Eye Disease: A Pilot Study” in the journal Clinical Ophthalmology.

In the study, researchers utilized PROSE as a drug delivery device for preservative-free cyclosporine 0.05% for the treatment of dry eye disease. To our knowledge, this report is the first to ever describe a prospective clinical trial utilizing a pharmaceutical in this manner. This study sets forth the template, concepts, and questions that are open to further investigation in this exciting area of drug delivery.

Ultimately, in the future, we hope this concept and research will lead to an additional ocular management strategy that will utilize the PROSE and SCLERAL platforms as drug delivery devices to open new avenues to improve ocular health and to improve the lives of our patients.

The study authors include staff from BostonSight, Tufts University School of Medicine, and the Department of Mathematical Sciences at Worcester Polytechnic Institute (WPI): Monica Nabil Nakhla, Ria Patel, Estelle Crowley, Yichen Li, Thelge Buddika Peiris, and Daniel Brocks.

Transforming Corneal Care with Dr. Dan Brocks

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Dr. Dan Brocks joined the OIS podcast with host Dr. Robert Rothman to discuss the unique PROSE lenses that are redefining corneal care and how BostonSight’s nonprofit mission is making advanced treatments accessible to more patients.

Key takeaways include:

PROSE Lenses: Customized scleral lenses that protect, hydrate, and restore vision for complex eye conditions.
Increased Accessibility: BostonSight’s new tech-driven approach to simplify lens fitting for broader use.
Mission-Driven Impact: How BostonSight reinvests revenue to offer free care and support for patients in need.

Listen to the podcast here.

Dr. Dan Brocks Featured Expert in First for Women Article on Wearing Contact Lenses in the Shower

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Dr. Dan Brocks, BostonSight’s Chief Medical Officer, is a featured expert in an article for First for Women, a lifestyle magazine.  Titled “Can You Shower With Contacts? How to Protect Your Vision and Prevent Infections,” Dr. Brocks shares important information about the dangers of water and contact lenses:

“Water can harbor dangerous bacteria, including a very destructive organism called acanthamoeba,” explains Dan Brocks, MD, chief medical officer at BostonSight. “If the bacteria or parasites get trapped underneath your contact lens, you could end up with a serious eye infection [called acanthamoeba keratitis] that has a high risk of causing blindness.”

Read the full article here.